| Gene Information | |
|---|---|
| Gene Name | LTB4R2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Leukotriene B4 receptor 2 (LTB4-R 2) (LTB4-R2) (LTB4 receptor JULF2) (Leukotriene B4 receptor BLT2) (Seven transmembrane receptor BLTR2) |
| Target Name | leukotriene b4 receptor 2 |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000213906 ) 3 ( ENSG00000285203 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NPC1 |
| Gene Card | LTB4R2 |
| Uniprot ID | Q9NPC1 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000048397) |
| Ortholog in Animals | Alpaca_ LTB4R2 ( ortholog_one2one ) Dog_ LTB4R2 ( ortholog_one2one ) Macaque_ LTB4R2 ( ortholog_one2one ) Mouse_ Ltb4r2 ( ortholog_one2one ) Pig_ LTB4R2 ( ortholog_one2one ) Rat_ Ltb4r2 ( ortholog_one2one ) Rabbit_ LTB4R2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LTB4R, SSTR5, SSTR4, NPBWR1, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, SSTR3, CMKLR2, SSTR1, KISS1R, UTS2R, NPBWR2, SSTR2, OPRD1 |
| Tissue | skin, tongue, zone.of.skin |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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