| Gene Information | |
|---|---|
| Gene Name | GLYAT |
| Organism | Homo sapiens (Human) |
| Gene Length | 296 |
| Protein Names | Glycine N-acyltransferase (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase) (AAc) (Aralkyl acyl-CoA N-acyltransferase) (Aralkyl acyl-CoA:amino acid N-acyltransferase) (Benzoyl-coenzyme A:glycine N-acyltransferase) (Glycine N-benzoyltransferase) (EC 2.3.1.71) (HRP-1(CLP)) |
| Target Name | glycine n-acyltransferase |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000149124 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6IB77 |
| Gene Card | GLYAT |
| Uniprot ID | Q6IB77 |
| Pfam | PF08444; PF06021 |
| In ASD | no |
| Allosteric Prediction | yes (0.096762723) |
| Ortholog in Animals | Alpaca_ GLYAT ( ortholog_one2one ) Dog_ GLYAT ( ortholog_one2one ) GuineaPig_ GLYAT ( ortholog_one2one ) Macaque_ GLYAT ( ortholog_one2one ) Mouse_ Glyat ( ortholog_one2one ) Pig_ GLYAT ( ortholog_one2one ) Rat_ Glyat ( ortholog_one2one ) Rabbit_ GLYAT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GLYATL2, GLYATL1B, GLYATL1, GLYATL3 |
| Tissue | kidney, liver |
| Tissue Specificity | Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. {ECO:0000269|PubMed:22475485}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10896818 rs675815 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:22475485}. |
| Mouse PG classification | NA |
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