| Gene Information | |
|---|---|
| Gene Name | WDR54 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | WD repeat-containing protein 54 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000005448 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H977 |
| Gene Card | WDR54 |
| Uniprot ID | Q9H977 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-2.040096061) |
| Ortholog in Animals | Alpaca_ WDR54 ( ortholog_one2one ) Dog_ WDR54 ( ortholog_one2one ) GuineaPig_ WDR54 ( ortholog_one2one ) Macaque_ WDR54 ( ortholog_one2one ) Mouse_ Wdr54 ( ortholog_one2one ) Pig_ WDR54 ( ortholog_one2one ) Rat_ Wdr54 ( ortholog_one2one ) Rabbit_ WDR54 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXW12, FBXW11, WDR49, FBXO36, BTRC, FBXW8, PAAF1, WDR64, EFCAB8, WDR86, FBXO16, TRAF7, FBXW9, FBXW7 |
| Tissue | NA |
| Tissue Specificity | Expressed in epithelial cells (at protein level) (PubMed:29987896). Isoform 3 expression is highly increased in colorectal cancer cells (PubMed:29987896). {ECO:0000269|PubMed:29987896}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Vesicle {ECO:0000269|PubMed:30458214}. Note=Aggregates in vesicles when cross-linked. {ECO:0000269|PubMed:30458214}. |
| Mouse PG classification | NA |
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