| Gene Information | |
|---|---|
| Gene Name | POLE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2286 |
| Protein Names | DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q07864 |
| Gene Card | POLE |
| Uniprot ID | Q07864 |
| Pfam | PF00136; PF03104; PF08490 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004115(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5VBN (X-ray 2.35A ) 7PFO (EM 3.20A ) 7PLO (EM 2.80A ) |
| DBSNP | rs34047482 rs5744739 rs1060500835 rs5744751 rs5744752 rs1057519943 rs1057519943 rs5744760 rs1057519945 rs483352909 rs864622766 rs5744799 rs1064794759 rs747692201 rs770558983 rs5744904 rs5744933 rs5744934 rs5744935 rs5744948 rs5744950 rs1335665224 rs5744971 rs5744991 rs5745021 rs58916399 rs5745066 rs5745067 rs5745068 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
| click here to return to the previous page | |