| Gene Information | |
|---|---|
| Gene Name | PRCP |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) |
| Target Name | prolylcarboxypeptidase |
| Target Type | Patented-recorded target |
| Gene Age | 680 ( ENSG00000137509 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P42785 |
| Gene Card | PRCP |
| Uniprot ID | P42785 |
| Pfam | PF05577 |
| In ASD | no |
| Allosteric Prediction | yes (0.164912834) |
| Ortholog in Animals | Alpaca_ PRCP ( ortholog_one2one ) Dog_ PRCP ( ortholog_one2one ) GuineaPig_ PRCP ( ortholog_one2one ) Macaque_ PRCP ( ortholog_one2one ) Mouse_ Prcp ( ortholog_one2one ) Pig_ PRCP ( ortholog_one2one ) Rat_ Prcp ( ortholog_one2one ) Rabbit_ PRCP ( ortholog_one2one ) |
| Ohnologs | DPP7 |
| Paralogs | DPP7, PRSS16 |
| Tissue | NA |
| Tissue Specificity | Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3N2Z (X-ray 2.79A ) |
| DBSNP | rs2229437 rs2228312 |
| Subcellular location [CC] | Lysosome. |
| Mouse PG classification | NA |
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