| Gene Information | |
|---|---|
| Gene Name | IQCG |
| Organism | Homo sapiens (Human) |
| Gene Length | 443 |
| Protein Names | Dynein regulatory complex protein 9 (IQ domain-containing protein G) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000114473 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H095 |
| Gene Card | IQCG |
| Uniprot ID | Q9H095 |
| Pfam | PF00612 |
| In ASD | no |
| Allosteric Prediction | no (-1.285066208) |
| Ortholog in Animals | Alpaca_ IQCG ( ortholog_one2one ) Dog_ IQCG ( ortholog_one2one ) GuineaPig_ IQCG ( ortholog_one2one ) Macaque_ IQCG ( ortholog_one2one ) Mouse_ Iqcg ( ortholog_one2one ) Pig_ IQCG ( ortholog_one2one ) Rat_ Iqcg ( ortholog_one2one ) Rabbit_ IQCG ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | oviduct, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4LZX (X-ray 1.50A ) 4M1L (X-ray 2.10A ) |
| DBSNP | rs9880989 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:24787902}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q80W32}. Cell projection, cilium {ECO:0000250|UniProtKB:Q80W32}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q80W32}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8HQ54}. Note=First detected in the cytoplasm of pachytene spermatocytes. Colocalizes with alpha-tubulin at the manchette in developing spermatids. Detected in the flagellum of mature testicular spermatozoa, and in the flagellum and post-acrosomal region of the head of epididymal spermatozoa. Detected in cilia in trachea and oviduct. {ECO:0000250|UniProtKB:Q80W32}. |
| Mouse PG classification | NA |
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