| Gene Information | |
|---|---|
| Gene Name | ACP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 426 |
| Protein Names | Testicular acid phosphatase (EC 3.1.3.2) (Acid phosphatase 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000142513 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BZG2 |
| Gene Card | ACP4 |
| Uniprot ID | Q9BZG2 |
| Pfam | PF00328 |
| In ASD | no |
| Allosteric Prediction | no (-0.588344681) |
| Ortholog in Animals | Alpaca_ ACP4 ( ortholog_one2one ) Dog_ ACP4 ( ortholog_one2one ) GuineaPig_ ACP4 ( ortholog_one2one ) Mouse_ Acp4 ( ortholog_one2one ) Pig_ ACP4 ( ortholog_one2one ) Rat_ Acp4 ( ortholog_one2one ) |
| Ohnologs | ACP3, ACP2 |
| Paralogs | ACP2, FRA10AC1, ACP6, PXYLP1, ACP3 |
| Tissue | NA |
| Tissue Specificity | Expressed mainly in the testis. Also expressed in the brain where they are enriched at the postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle. Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is expressed in the testis, trachea, prostate and bone marrow. {ECO:0000269|PubMed:11414767}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs902112287 rs202073531 rs767907487 rs779823931 rs763573828 |
| Subcellular location [CC] | Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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