| Gene Information | |
|---|---|
| Gene Name | GCNT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 438 |
| Protein Names | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000140297 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95395 |
| Gene Card | GCNT3 |
| Uniprot ID | O95395 |
| Pfam | PF02485 |
| In ASD | no |
| Allosteric Prediction | no (-1.068137757) |
| Ortholog in Animals | Alpaca_ GCNT3 ( ortholog_one2one ) Dog_ GCNT3 ( ortholog_one2one ) GuineaPig_ GCNT3 ( ortholog_one2one ) Macaque_ GCNT3 ( ortholog_one2one ) Mouse_ Gcnt3 ( ortholog_one2one ) Pig_ GCNT3 ( ortholog_one2one ) Rat_ Gcnt3 ( ortholog_one2one ) Rabbit_ GCNT3 ( ortholog_one2one ) |
| Ohnologs | GCNT4, GCNT1 |
| Paralogs | WSCD1, GCNT2, GCNT7, XYLT1, GCNT1, GCNT4, XYLT2, WSCD2 |
| Tissue | minor.salivary.gland, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced. {ECO:0000269|PubMed:17303715, ECO:0000269|PubMed:9915862}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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