| Gene Information | |
|---|---|
| Gene Name | SMS |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Spermine synthase (SPMSY) (EC 2.5.1.22) (Spermidine aminopropyltransferase) |
| Target Name | spermine synthase |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000102172 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P52788 |
| Gene Card | SMS |
| Uniprot ID | P52788 |
| Pfam | PF17284; PF17950 |
| In ASD | no |
| Allosteric Prediction | yes (0.044112977) |
| Ortholog in Animals | Alpaca_ SMS ( ortholog_one2one ) Macaque_ SMS ( ortholog_one2one ) Mouse_ Sms ( ortholog_one2one ) Pig_ SMS ( ortholog_one2one ) Rat_ AABR07054361.1 ( ortholog_one2many ) Rat_ Sms ( ortholog_one2many ) Rat_ AABR07021734.1 ( ortholog_one2many ) Rabbit_ SMS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SRM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3C6K (X-ray 1.95A ) 3C6M (X-ray 2.45A ) |
| DBSNP | rs121434610 rs397515549 rs1394834572 rs397515550 rs267607076 rs397515553 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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