| Gene Information | |
|---|---|
| Gene Name | CD305 |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6GTX8 |
| Gene Card | LAIR1 |
| Uniprot ID | Q6GTX8 |
| Pfam | PF13895 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells. Highly expressed in naive T-cells and B-cells but no expression on germinal center B-cells. Abnormally low expression in naive B-cells from HIV-1 infected patients. Very low expression in NK cells from a patient with chronic active Epstein-Barr virus infection. {ECO:0000269|PubMed:10540327, ECO:0000269|PubMed:12757266, ECO:0000269|PubMed:14604962, ECO:0000269|PubMed:15950745}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3KGR (X-ray 1.80A ) 3RP1 (X-ray 2.60A ) 7F9L (X-ray 2.70A ) 7F9M (X-ray 2.90A ) 7F9N (X-ray 3.00A ) |
| DBSNP | rs3745442 rs118056835 rs79046875 rs190462445 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10229813, ECO:0000269|PubMed:11160222, ECO:0000269|PubMed:9285412}; Single-pass type I membrane protein {ECO:0000269|PubMed:10229813, ECO:0000269|PubMed:11160222, ECO:0000269|PubMed:9285412}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |