| Gene Information | |
|---|---|
| Gene Name | CDH13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 713 |
| Protein Names | Cadherin-13 (Heart cadherin) (H-cadherin) (P105) (Truncated cadherin) (T-cad) (T-cadherin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140945 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P55290 |
| Gene Card | CDH13 |
| Uniprot ID | P55290 |
| Pfam | PF00028; PF08758 |
| In ASD | no |
| Allosteric Prediction | no (-0.222915849) |
| Ortholog in Animals | Alpaca_ CDH13 ( ortholog_one2one ) Dog_ CDH13 ( ortholog_one2one ) GuineaPig_ CDH13 ( ortholog_one2one ) Macaque_ CDH13 ( ortholog_one2one ) Mouse_ Cdh13 ( ortholog_one2one ) Pig_ CDH13 ( ortholog_one2one ) Rat_ Cdh13 ( ortholog_one2one ) Rabbit_ CDH13 ( ortholog_one2one ) |
| Ohnologs | DSG2, CDH19, CDH7, CDH20, CDH26, DSC2, DSG3, DSC3, DSC1, CDH22, CDH8, CDH2, DSG4, CDH4, CDH1, CDH10, CDH3, CDH9, CDH6, CDH11, CDH18, CDH12 |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord. {ECO:0000269|PubMed:10737605, ECO:0000269|PubMed:8673923}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V37 (NMR - ) |
| DBSNP | rs368685803 rs199539898 rs183971768 rs7197352 rs377210458 rs200000145 rs35549391 rs34106627 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor. |
| Mouse PG classification | NA |
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