| Gene Information | |
|---|---|
| Gene Name | KRTA |
| Organism | Homo sapiens (Human) |
| Gene Length | 644 |
| Protein Names | Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P04264 |
| Gene Card | KRT1 |
| Uniprot ID | P04264 |
| Pfam | PF00038; PF16208; PF16210 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | The source of this protein is neonatal foreskin. The 67-kDa type II keratins are expressed in terminally differentiating epidermis. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ZRY (X-ray 3.30A ) 6E2J (X-ray 2.39A ) 6UUI (X-ray 2.07A ) |
| DBSNP | rs57977969 rs57959072 rs57959072 rs57695159 rs60022878 rs59429455 rs58928370 rs58928370 rs60937700 rs61549035 rs58062863 rs1050872 rs17678945 rs59089201 rs61218439 rs57837128 rs58420087 rs267607430 rs56914602 rs60279707 rs60279707 rs14024 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17956333}. Cytoplasm {ECO:0000269|PubMed:32179842}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |