| Gene Information | |
|---|---|
| Gene Name | KRT86 |
| Organism | Homo sapiens (Human) |
| Gene Length | 486 |
| Protein Names | Keratin, type II cuticular Hb6 (Hair keratin K2.11) (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 86 ( ENSG00000170442 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43790 |
| Gene Card | KRT86 |
| Uniprot ID | O43790 |
| Pfam | PF00038; PF16208 |
| In ASD | no |
| Allosteric Prediction | no (-1.506116323) |
| Ortholog in Animals | Alpaca_ KRT86 ( ortholog_one2one ) Dog_ KRT85 ( ortholog_one2many ) Macaque_ KRT86 ( ortholog_one2one ) |
| Ohnologs | GFAP, KRT19, KRT15, KRT10, KRT17P2, KRT16, KRT14, VIM, DES |
| Paralogs | KRT81, KRT83, VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT80, KRT33B, KRT31, KRT77, KRT26, KRT32, KRT73, KRT28, KRT37, KRT38, KRT6B, KRT6A, KRT6C, KRT72, KRT20, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT14, KRT16, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10 |
| Tissue | NA |
| Tissue Specificity | Synthesis begins slightly higher in the hair shaft than HB1 and HB3 and continues much farther up, ending in the keratogeneous zone. {ECO:0000269|PubMed:9084137}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs61091894 rs61091894 rs60687604 rs60687604 rs121909130 rs121909129 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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