Gene Information
Gene NameNSMCE1
OrganismHomo sapiens (Human)
Gene Length266
Protein NamesNon-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000169189 )
Evolutionary StageEukaryota
AlphaFoldDBQ8WV22
Gene CardNSMCE1
Uniprot IDQ8WV22
PfamPF07574; PF08746
In ASDno
Allosteric Predictionno (-1.460240507)
Ortholog in AnimalsAlpaca_ NSMCE1 ( ortholog_one2one )
Dog_ NSMCE1 ( ortholog_one2one )
GuineaPig_ NSMCE1 ( ortholog_one2one )
Macaque_ NSMCE1 ( ortholog_one2one )
Mouse_ Nsmce1 ( ortholog_one2one )
Pig_ NSMCE1 ( ortholog_one2one )
Rat_ Nsmce1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.062834(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CT0  (NMR  5HVQ  (X-ray  2.92A  5WY5  (X-ray  2.92A 
DBSNP rs7195194  rs17856580 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000305|PubMed:18086888}.
Mouse PG classificationNA
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