| Gene Information | |
|---|---|
| Gene Name | KRT80 |
| Organism | Homo sapiens (Human) |
| Gene Length | 452 |
| Protein Names | Keratin, type II cytoskeletal 80 (Cytokeratin-80) (CK-80) (Keratin-80) (K80) (Type-II keratin Kb20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000167767 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6KB66 |
| Gene Card | KRT80 |
| Uniprot ID | Q6KB66 |
| Pfam | PF00038 |
| In ASD | no |
| Allosteric Prediction | no (-1.073308298) |
| Ortholog in Animals | Alpaca_ KRT80 ( ortholog_one2one ) Dog_ KRT80 ( ortholog_one2one ) GuineaPig_ KRT80 ( ortholog_one2one ) Macaque_ KRT80 ( ortholog_one2one ) Mouse_ Krt80 ( ortholog_one2one ) Pig_ KRT80 ( ortholog_one2one ) Rat_ Krt80 ( ortholog_one2one ) Rabbit_ KRT80 ( ortholog_one2one ) |
| Ohnologs | KRT33A, GFAP, KRT15, KRT17P2, KRT16, KRT14, VIM, DES |
| Paralogs | VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT33B, KRT31, KRT77, KRT26, KRT32, KRT73, KRT28, KRT37, KRT38, KRT6B, KRT6A, KRT6C, KRT72, KRT20, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, KRT86, KRT83, KRT81, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT14, KRT16, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10 |
| Tissue | skin, lower.leg.skin, suprapubic.skin |
| Tissue Specificity | Weakly expressed in tongue, but not skin or in any other tissues or organs examined. {ECO:0000269|PubMed:15737194}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35725856 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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