| Gene Information | |
|---|---|
| Gene Name | STXBP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 592 |
| Protein Names | Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000116266 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00186 |
| Gene Card | STXBP3 |
| Uniprot ID | O00186 |
| Pfam | PF00995 |
| In ASD | no |
| Allosteric Prediction | no (-0.090608037) |
| Ortholog in Animals | Alpaca_ STXBP3 ( ortholog_one2one ) Dog_ STXBP3 ( ortholog_one2one ) GuineaPig_ STXBP3 ( ortholog_one2one ) Macaque_ STXBP3 ( ortholog_one2one ) Mouse_ Stxbp3 ( ortholog_one2one ) Pig_ STXBP3 ( ortholog_one2one ) Rat_ Stxbp3 ( ortholog_one2one ) Rabbit_ STXBP3 ( ortholog_one2one ) |
| Ohnologs | STXBP2, STXBP1 |
| Paralogs | SCFD2, VPS33A, STXBP2, VPS33B, SCFD1, STXBP1, VPS45 |
| Tissue | NA |
| Tissue Specificity | Megakaryocytes and platelets. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2275344 rs1044136 rs1044137 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:10194441}. Cell membrane {ECO:0000269|PubMed:10194441}. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated. |
| Mouse PG classification | NA |
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