| Gene Information | |
|---|---|
| Gene Name | KRT6C |
| Organism | Homo sapiens (Human) |
| Gene Length | 564 |
| Protein Names | Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000170465 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P48668 |
| Gene Card | KRT6C |
| Uniprot ID | P48668 |
| Pfam | PF00038; PF16208 |
| In ASD | no |
| Allosteric Prediction | no (-1.793265905) |
| Ortholog in Animals | Alpaca_ KRT6C ( ortholog_one2one ) Mouse_ Krt6b ( ortholog_many2many ) Mouse_ Krt6a ( ortholog_many2many ) Mouse_ Gm5414 ( ortholog_many2many ) Rat_ Krt6a ( ortholog_many2many ) Rat_ AABR07001416.1 ( ortholog_many2many ) |
| Ohnologs | KRT33A, GFAP, KRT19, KRT15, KRT10, KRT17P2, KRT16, KRT14, VIM, DES |
| Paralogs | VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT80, KRT33B, KRT31, KRT77, KRT26, KRT32, KRT73, KRT28, KRT37, KRT38, KRT72, KRT20, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, KRT86, KRT83, KRT81, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT14, KRT16, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10, KRT6B, KRT6A |
| Tissue | esophagus, cervix, tongue, esophagus.mucosa |
| Tissue Specificity | Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs11608915 rs17099602 rs587777292 rs412533 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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