| Gene Information | |
|---|---|
| Gene Name | KRT26 |
| Organism | Homo sapiens (Human) |
| Gene Length | 468 |
| Protein Names | Keratin, type I cytoskeletal 26 (Cytokeratin-26) (CK-26) (Keratin-25B) (K25B) (Keratin-26) (K26) (Type I inner root sheath-specific keratin-K25irs2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000186393 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7Z3Y9 |
| Gene Card | KRT26 |
| Uniprot ID | Q7Z3Y9 |
| Pfam | PF00038 |
| In ASD | no |
| Allosteric Prediction | no (-0.928987795) |
| Ortholog in Animals | Alpaca_ KRT26 ( ortholog_one2one ) Dog_ KRT26 ( ortholog_one2one ) GuineaPig_ KRT26 ( ortholog_one2one ) Macaque_ KRT26 ( ortholog_one2one ) Mouse_ Krt26 ( ortholog_one2one ) Pig_ KRT26 ( ortholog_one2one ) Rat_ Krt26 ( ortholog_one2one ) Rabbit_ KRT26 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT80, KRT33B, KRT31, KRT77, KRT32, KRT73, KRT28, KRT37, KRT38, KRT6B, KRT6A, KRT6C, KRT72, KRT20, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, KRT86, KRT83, KRT81, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT14, KRT16, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10 |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in skin and scalp, and weak expression observed in thymus and tongue. In the hair follicle, expression is restricted to the mid- to upper inner root sheath cuticle, being present slightly above the apex of the dermal papilla (at protein level). {ECO:0000269|PubMed:15617563, ECO:0000269|PubMed:16874310}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9898164 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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