Gene Information
Gene NameKRT25C
OrganismHomo sapiens (Human)
Gene Length459
Protein NamesKeratin, type I cytoskeletal 27 (Cytokeratin-27) (CK-27) (Keratin-25C) (K25C) (Keratin-27) (K27) (Type I inner root sheath-specific keratin-K25irs3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ7Z3Y8
Gene CardKRT27
Uniprot IDQ7Z3Y8
PfamPF00038
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityStrongly expressed in skin and scalp. In the hair follicle, expressed in Henle layer, Huxley layer and in the inner root sheath cuticle of the hair follicle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also present in the medulla of beard hair (at protein level). {ECO:0000269|PubMed:15617563, ECO:0000269|PubMed:16874310}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2469826  rs12453124  rs17558560  rs17558532  rs981684 
Subcellular location [CC]Cytoplasm {ECO:0000250|UniProtKB:Q9Z320}.
Mouse PG classificationNA
click here to return to the previous page