| Gene Information | |
|---|---|
| Gene Name | ATP6V1C1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 382 |
| Protein Names | V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1) |
| Target Name | v-atpase subunits |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000155097 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P21283 |
| Gene Card | ATP6V1C1 |
| Uniprot ID | P21283 |
| Pfam | PF03223 |
| In ASD | no |
| Allosteric Prediction | yes (0.042713071) |
| Ortholog in Animals | Alpaca_ ATP6V1C1 ( ortholog_one2one ) Dog_ ATP6V1C1 ( ortholog_one2one ) GuineaPig_ ATP6V1C1 ( ortholog_one2one ) Macaque_ ATP6V1C1 ( ortholog_one2one ) Mouse_ Atp6v1c1 ( ortholog_one2one ) Pig_ ATP6V1C1 ( ortholog_one2one ) Rat_ Atp6v1c1 ( ortholog_one2one ) Rabbit_ ATP6V1C1 ( ortholog_one2one ) |
| Ohnologs | ATP6V1C2 |
| Paralogs | ATP6V1C2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12384298}. |
| Pharmacological Animal Models | 0.312235(Chimpanzee);0.219012(Mouse);0.048918(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WM2 (EM 3.10A ) 6WM3 (EM 3.40A ) 6WM4 (EM 3.60A ) 7U4T (EM 3.60A ) 7UNF (EM 4.08A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q5FVI6}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:Q5FVI6}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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