Gene Information
Gene NameMETTL4
OrganismHomo sapiens (Human)
Gene Length472
Protein NamesN(6)-adenine-specific methyltransferase METTL4 (Methyltransferase-like protein 4) (N(6)-adenine-specific DNA methyltransferase METTL4) (EC 2.1.1.72) (snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4) (EC 2.1.1.-)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000101574 )
Evolutionary StageEukaryota
AlphaFoldDBQ8N3J2
Gene CardMETTL4
Uniprot IDQ8N3J2
PfamPF05063
In ASDno
Allosteric Predictionno (-0.646539752)
Ortholog in AnimalsAlpaca_ METTL4 ( ortholog_one2one )
Dog_ METTL4 ( ortholog_one2one )
GuineaPig_ METTL4 ( ortholog_one2one )
Macaque_ METTL4 ( ortholog_one2one )
Mouse_ Mettl4 ( ortholog_one2one )
Pig_ METTL4 ( ortholog_one2one )
Rat_ Mettl4 ( ortholog_one2one )
Rabbit_ METTL4 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs12606220  rs34143130  rs2677879  rs8084295 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:31913360, ECO:0000269|PubMed:32183942}. Cytoplasm, cytosol {ECO:0000269|PubMed:32183942}. Mitochondrion matrix {ECO:0000269|PubMed:32183942}.
Mouse PG classificationNA
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