| Gene Information | |
|---|---|
| Gene Name | GCLM |
| Organism | Homo sapiens (Human) |
| Gene Length | 274 |
| Protein Names | Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit) |
| Target Name | glutamate--cysteine ligase regulatory subunit |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000023909 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P48507 |
| Gene Card | GCLM |
| Uniprot ID | P48507 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | yes (0.210858484) |
| Ortholog in Animals | Alpaca_ GCLM ( ortholog_one2one ) Dog_ GCLM ( ortholog_one2one ) Macaque_ GCLM ( ortholog_one2one ) Mouse_ Gclm ( ortholog_one2one ) Pig_ GCLM ( ortholog_one2one ) Rat_ Gclm ( ortholog_one2one ) Rabbit_ GCLM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | In all tissues examined. Highest levels in skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17880087 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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