Gene Information
Gene NameKRT16
OrganismHomo sapiens (Human)
Gene Length473
Protein NamesKeratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Target Namekeratin, type i cytoskeletal 16
Target TypeNA
Gene Age382 ( ENSG00000186832 )
Evolutionary StageEumetazoa
AlphaFoldDBP08779
Gene CardKRT16
Uniprot IDP08779
PfamPF00038
In ASDno
Allosteric Predictionno (-0.66619402)
Ortholog in AnimalsAlpaca_ KRT16 ( ortholog_one2one )
Macaque_ KRT16 ( ortholog_one2one )
Mouse_ Krt16 ( ortholog_one2one )
Rat_ Krt15 ( ortholog_one2one )
Rabbit_ KRT16 ( ortholog_one2one )
OhnologsVIM, NEFM, KRT18, PRPH, KRT7, INA, KRT84, KRT82, KRT80, KRT1, KRT8, KRT86, KRT75, KRT6C, KRT4, KRT83, KRT2, DES, KRT6B, KRT79, KRT5, KRT77, KRT6A
ParalogsKRT14, VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT80, KRT33B, KRT31, KRT77, KRT26, KRT32, KRT73, KRT28, KRT37, KRT38, KRT6B, KRT6A, KRT6C, KRT72, KRT20, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, KRT86, KRT83, KRT81, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10
Tissueesophagus, tongue, esophagus.mucosa
Tissue SpecificityExpressed in the corneal epithelium (at protein level). {ECO:0000269|PubMed:26758872}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs28928894  rs59349773  rs58293603  rs58293603  rs58293603  rs58608173  rs587777717  rs60723330  rs59856285  rs57424749  rs28928895  rs60944949  rs59328451 
Subcellular location [CC]NA
Mouse PG classificationHPG
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