| Gene Information | |
|---|---|
| Gene Name | CAPN13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 669 |
| Protein Names | Calpain-13 (EC 3.4.22.-) (Calcium-activated neutral proteinase 13) (CANP 13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000162949 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6MZZ7 |
| Gene Card | CAPN13 |
| Uniprot ID | Q6MZZ7 |
| Pfam | PF01067; PF00648 |
| In ASD | no |
| Allosteric Prediction | no (-0.672222116) |
| Ortholog in Animals | Alpaca_ CAPN13 ( ortholog_one2one ) Dog_ CAPN13 ( ortholog_one2one ) GuineaPig_ CAPN13 ( ortholog_one2one ) Macaque_ CAPN13 ( ortholog_one2one ) Mouse_ Capn13 ( ortholog_one2one ) Pig_ CAPN13 ( ortholog_one2one ) Rat_ Capn13 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CAPN1, PEF1, GCA, SRI, CAPN9, PDCD6, CAPN2, CAPN5, CAPN14, CAPN15, CAPN7, ADGB, CAPN6, CAPN8, CAPN3, CAPN12, CAPNS2, CAPN11, CAPNS1, CAPN10 |
| Tissue | duodenum, rectum, small.intestine, stomach, colon, gall.bladder, lung, pancreas |
| Tissue Specificity | Weakly expressed in lung and testis. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:11675017}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I7A (X-ray 1.80A ) |
| DBSNP | rs17010210 rs508405 rs2276568 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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