| Gene Information | |
|---|---|
| Gene Name | KRR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | KRR1 small subunit processome component homolog (HIV-1 Rev-binding protein 2) (KRR-R motif-containing protein 1) (Rev-interacting protein 1) (Rip-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000111615 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q13601 |
| Gene Card | KRR1 |
| Uniprot ID | Q13601 |
| Pfam | PF17903 |
| In ASD | no |
| Allosteric Prediction | no (-1.156327576) |
| Ortholog in Animals | Alpaca_ KRR1 ( ortholog_one2one ) Dog_ KRR1 ( ortholog_one2one ) GuineaPig_ KRR1 ( ortholog_one2one ) Macaque_ KRR1 ( ortholog_one2one ) Mouse_ Krr1 ( ortholog_one2one ) Pig_ KRR1 ( ortholog_one2one ) Rat_ Krr1 ( ortholog_one2one ) Rabbit_ KRR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453561(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) |
| DBSNP | rs11540407 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|Ref.6}. Nucleus {ECO:0000269|Ref.6}. Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. Note=Translocates from cytoplasm to nucleus after exposure to HIV-1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR (Ref.6). |
| Mouse PG classification | NA |
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