| Gene Information | |
|---|---|
| Gene Name | SPATA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Spermatogenesis-associated protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000158480 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UM82 |
| Gene Card | SPATA2 |
| Uniprot ID | Q9UM82 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.74706497) |
| Ortholog in Animals | Alpaca_ SPATA2 ( ortholog_one2one ) Dog_ SPATA2 ( ortholog_one2one ) GuineaPig_ SPATA2 ( ortholog_one2one ) Macaque_ SPATA2 ( ortholog_one2one ) Mouse_ Spata2 ( ortholog_one2one ) Pig_ SPATA2 ( ortholog_one2one ) Rat_ Spata2 ( ortholog_one2one ) Rabbit_ SPATA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SPATA2L |
| Tissue | NA |
| Tissue Specificity | Present at high level in Sertoli cells, but not detected in spermatogenic cells (at protein level) (PubMed:10222154, PubMed:11079456). Low expression in spleen, thymus and prostate (PubMed:10222154). {ECO:0000269|PubMed:10222154, ECO:0000269|PubMed:11079456}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LJM (X-ray 1.45A ) 5LJN (X-ray 2.70A ) |
| DBSNP | rs2072985 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10222154, ECO:0000269|PubMed:11079456}. Nucleus {ECO:0000250|UniProtKB:Q66HP6}. Note=Detected in the tubular compartment of the testis and, in the cytoplasm of the Sertoli cells. {ECO:0000269|PubMed:11079456}. |
| Mouse PG classification | NA |
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