| Gene Information | |
|---|---|
| Gene Name | CP |
| Organism | Homo sapiens (Human) |
| Gene Length | 1065 |
| Protein Names | Ceruloplasmin (EC 1.16.3.1) (Ferroxidase) |
| Target Name | ceruloplasmin |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000047457 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P00450 |
| Gene Card | CP |
| Uniprot ID | P00450 |
| Pfam | PF00394; PF07731; PF07732 |
| In ASD | no |
| Allosteric Prediction | yes (1.046927391) |
| Ortholog in Animals | Alpaca_ CP ( ortholog_one2one ) Dog_ CP ( ortholog_one2one ) GuineaPig_ CP ( ortholog_one2one ) Macaque_ CP ( ortholog_one2one ) Mouse_ Cp ( ortholog_one2one ) Pig_ CP ( ortholog_one2one ) Rat_ Cp ( ortholog_one2one ) Rabbit_ CP ( ortholog_one2one ) |
| Ohnologs | HEPH, HEPHL1 |
| Paralogs | CNTNAP3B, CNTNAP3, CNTNAP3C, CNTNAP4, PDGFD, ASTL, CNTNAP5, HEPH, MEP1A, NRXN2, CNTNAP2, MFRP, CUZD1, NETO2, TLL2, F5, PCOLCE, NRP1, NRXN3, EDIL3, CNTNAP1, CUBN, MEP1B, NETO1, MFGE8, PCOLCE2, NRP2, HEPHL1, F8, TLL1, NRXN1, DCBLD2, PDGFC, CDCP2, BMP1 |
| Tissue | liver, tricuspid.valve |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KCW (X-ray 3.00A ) 2J5W (X-ray 2.80A ) 4EJX (X-ray 4.69A ) 4ENZ (X-ray 2.60A ) |
| DBSNP | rs759185877 rs34624984 rs35331711 rs701753 rs61733458 rs115552500 rs56033670 |
| Subcellular location [CC] | Secreted. Note=Colocalizes with GCP1 in secretory intracellular compartments. {ECO:0000250}. |
| Mouse PG classification | NA |
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