Gene Information
Gene NameKREMEN1
OrganismHomo sapiens (Human)
Gene Length473
Protein NamesKremen protein 1 (Dickkopf receptor) (Kringle domain-containing transmembrane protein 1) (Kringle-containing protein marking the eye and the nose)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000183762 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96MU8
Gene CardKREMEN1
Uniprot IDQ96MU8
PfamPF00431; PF00051; PF01822
In ASDno
Allosteric Predictionno (-0.161948284)
Ortholog in AnimalsAlpaca_ KREMEN1 ( ortholog_one2one )
Dog_ KREMEN1 ( ortholog_one2one )
GuineaPig_ KREMEN1 ( ortholog_one2one )
Macaque_ KREMEN1 ( ortholog_one2one )
Mouse_ Kremen1 ( ortholog_one2one )
Pig_ KREMEN1 ( ortholog_one2one )
Rat_ Kremen1 ( ortholog_one2one )
Rabbit_ KREMEN1 ( ortholog_one2one )
OhnologsKREMEN2
ParalogsKREMEN2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.029817(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5FWS  (X-ray  1.90A  5FWT  (X-ray  2.10A  5FWU  (X-ray  2.80A  5FWV  (X-ray  3.20A  5FWW  (X-ray  3.50A  7BZT  (EM  3.00A  7BZU  (EM  3.00A 
DBSNP rs1057524917 
Subcellular location [CC]Cell membrane {ECO:0000250|UniProtKB:Q99N43};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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