| Gene Information | |
|---|---|
| Gene Name | MOCS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 636 |
| Protein Names | Molybdenum cofactor biosynthesis protein 1 (Cell migration-inducing gene 11 protein) (Molybdenum cofactor synthesis-step 1 protein A-B) [Includes: GTP 3',8-cyclase (EC 4.1.99.22) (Molybdenum cofactor biosynthesis protein A); Cyclic pyranopterin monophosphate synthase (EC 4.6.1.17) (Molybdenum cofactor biosynthesis protein C)] |
| Target Name | cyclic pyranopterin monophosphate synthase |
| Target Type | Clinical trial target |
| Gene Age | >4290 ( ENSG00000124615 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NZB8 |
| Gene Card | MOCS1 |
| Uniprot ID | Q9NZB8 |
| Pfam | PF01967; PF06463; PF04055 |
| In ASD | no |
| Allosteric Prediction | yes (0.144463361) |
| Ortholog in Animals | Alpaca_ MOCS1 ( ortholog_one2one ) Dog_ MOCS1 ( ortholog_one2one ) GuineaPig_ MOCS1 ( ortholog_one2one ) Macaque_ MOCS1 ( ortholog_one2one ) Mouse_ Mocs1 ( ortholog_one2one ) Pig_ MOCS1 ( ortholog_one2one ) Rat_ Mocs1 ( ortholog_one2one ) Rabbit_ MOCS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform MOCS1A and isoform 2 are widely expressed. {ECO:0000269|PubMed:12208140, ECO:0000269|PubMed:9731530}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs754441164 rs104893970 rs151141411 rs779592342 rs372246702 rs104893969 rs1187685038 rs762253951 rs11969769 rs11969206 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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