| Gene Information | |
|---|---|
| Gene Name | KPP |
| Organism | Homo sapiens (Human) |
| Gene Length | 584 |
| Protein Names | Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P13645 |
| Gene Card | KRT10 |
| Uniprot ID | P13645 |
| Pfam | PF00038 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Seen in all suprabasal cell layers including stratum corneum. Expressed on the surface of lung cell lines (PubMed:19627498). Localized on the surface of desquamated nasal epithelial cells (at protein level) (PubMed:12427098). {ECO:0000269|PubMed:12427098, ECO:0000269|PubMed:19627498}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ASW (X-ray 2.60A ) 4F1Z (X-ray 2.30A ) 4ZRY (X-ray 3.30A ) 6E2J (X-ray 2.39A ) 6EC0 (X-ray 2.98A ) 6UUI (X-ray 2.07A ) |
| DBSNP | rs4261597 rs77919366 rs58901407 rs58901407 rs57784225 rs58852768 rs58075662 rs58075662 rs58852768 rs58414354 rs58735429 rs60118264 rs59075499 rs61434181 rs58026994 rs62651994 rs267607383 rs17855579 |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000269|PubMed:12427098}. Cell surface {ECO:0000269|PubMed:19627498}. Cytoplasm {ECO:0000269|PubMed:32179842}. |
| Mouse PG classification | NA |
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