| Gene Information | |
|---|---|
| Gene Name | KPNA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 521 |
| Protein Names | Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000102753 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O00505 |
| Gene Card | KPNA3 |
| Uniprot ID | O00505 |
| Pfam | PF00514; PF16186; PF01749 |
| In ASD | no |
| Allosteric Prediction | no (-0.163002192) |
| Ortholog in Animals | Alpaca_ KPNA3 ( ortholog_one2one ) Dog_ KPNA3 ( ortholog_one2one ) GuineaPig_ KPNA3 ( ortholog_one2one ) Macaque_ KPNA3 ( ortholog_one2one ) Mouse_ Kpna3 ( ortholog_one2one ) Pig_ KPNA3 ( ortholog_one2one ) Rat_ Kpna3 ( ortholog_one2one ) Rabbit_ KPNA3 ( ortholog_one2one ) |
| Ohnologs | KPNA4 |
| Paralogs | KPNA4, KPNA7, KPNA2, KPNA1, KPNA6, KPNA5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest levels in heart and skeletal muscle. |
| Pharmacological Animal Models | 0.024145(Chimpanzee);0.015544(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1043015 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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