| Gene Information | |
|---|---|
| Gene Name | KPL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1822 |
| Protein Names | Sperm flagellar protein 2 (Protein KPL2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9C093 |
| Gene Card | SPEF2 |
| Uniprot ID | Q9C093 |
| Pfam | PF06294 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6897513 rs34307272 rs16902381 rs34852821 rs34708521 rs7710284 rs12332369 rs13170082 rs13170390 rs2277044 |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:31048344, ECO:0000269|PubMed:31151990, ECO:0000269|PubMed:31278745}. Cytoplasm {ECO:0000250|UniProtKB:Q8C9J3}. Golgi apparatus {ECO:0000250|UniProtKB:Q8C9J3}. Note=Shows dynamic localization in developing spermatozoa. Localizes to the manchette in step 10-12 elongating spermatids. Detected in the basal body and neck area of step 13-14 spermatids. Localizes to the midpiece of the sperm tail in step 15-16 spermatids. During the epididymal transport of spermatozoa, expression in the sperm tail reduces and becomes concentrated at the distal part of the midpiece. Detected in the Golgi apparatus of late spermatocytes and round spermatids. Detected in the cytoplasm of Sertoli cells. {ECO:0000250|UniProtKB:Q8C9J3}. |
| Mouse PG classification | NA |
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