Gene Information
Gene NameKPI2
OrganismHomo sapiens (Human)
Gene Length1503
Protein NamesSerine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8IWU2
Gene CardLMTK2
Uniprot IDQ8IWU2
PfamPF07714
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityMainly expressed in skeletal muscle, and weakly in brain and pancreas. {ECO:0000269|PubMed:12393858}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.00599(Rat);0.100000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3735252  rs147940573  rs34461195  rs34628253  rs56204700  rs11765552  rs56196840  rs34005293  rs55867257  rs3801295  rs35912712  rs56343792  rs45488394 
Subcellular location [CC]Membrane {ECO:0000269|PubMed:23114966};
Multi-pass membrane protein {ECO:0000269|PubMed:23114966}.
Mouse PG classificationNA
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