| Gene Information | |
|---|---|
| Gene Name | NCOR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2514 |
| Protein Names | Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000196498 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y618 |
| Gene Card | NCOR2 |
| Uniprot ID | Q9Y618 |
| Pfam | PF15784; PF00249 |
| In ASD | no |
| Allosteric Prediction | yes (0.536026803) |
| Ortholog in Animals | Alpaca_ NCOR2 ( ortholog_one2one ) Dog_ NCOR2 ( ortholog_one2one ) GuineaPig_ NCOR2 ( ortholog_one2one ) Macaque_ NCOR2 ( ortholog_one2one ) Mouse_ Ncor2 ( ortholog_one2one ) Pig_ NCOR2 ( ortholog_one2one ) Rat_ Ncor2 ( ortholog_one2one ) Rabbit_ NCOR2 ( ortholog_one2one ) |
| Ohnologs | NCOR1 |
| Paralogs | NCOR1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. High levels of expression are detected in lung, spleen and brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.032727(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KKQ (X-ray 3.00A ) 1R2B (X-ray 2.20A ) 1XC5 (NMR - ) 2GPV (X-ray 2.85A ) 2L5G (NMR - ) 2LTP (NMR - ) 2ODD (NMR - ) 2RT5 (NMR - ) 3R29 (X-ray 2.90A ) 3R2A (X-ray 3.00A ) 4A69 (X-ray 2.06A ) 4OAR (X-ray 2.41A ) 5X8Q (X-ray 2.20A ) 5X8X (X-ray 2.60A ) 5ZOO (X-ray 1.85A ) 5ZOP (X-ray 2.70A ) 6A22 (X-ray 2.55A ) 6IVX (X-ray 2.35A ) 6PDZ (X-ray 2.10A ) |
| DBSNP | rs7978237 rs2229840 rs2230944 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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