| Gene Information | |
|---|---|
| Gene Name | KNS |
| Organism | Homo sapiens (Human) |
| Gene Length | 963 |
| Protein Names | Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P33176 |
| Gene Card | KIF5B |
| Uniprot ID | P33176 |
| Pfam | PF00225 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.023077(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BG2 (X-ray 1.80A ) 1MKJ (X-ray 2.70A ) 2P4N (EM 9.00A ) 3J8X (EM 5.00A ) 3J8Y (EM 5.00A ) 4HNA (X-ray 3.19A ) 4LNU (X-ray 2.19A ) 5LT0 (X-ray 2.00A ) 5LT1 (X-ray 1.95A ) 5LT2 (X-ray 2.60A ) 5LT3 (X-ray 2.59A ) 5LT4 (X-ray 2.88A ) 6OJQ (EM 3.67A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2PQA9}. Cytolytic granule membrane {ECO:0000269|PubMed:24088571}. Lysosome membrane {ECO:0000269|PubMed:22172677, ECO:0000269|PubMed:24088571}; Peripheral membrane protein {ECO:0000305|PubMed:22172677, ECO:0000305|PubMed:24088571}; Cytoplasmic side {ECO:0000305|PubMed:22172677, ECO:0000305|PubMed:24088571}. Note=Uniformly distributed between soma and neurites in hippocampal neurons. {ECO:0000250|UniProtKB:Q2PQA9}. |
| Mouse PG classification | NA |
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