Gene Information
Gene NameKNS
OrganismHomo sapiens (Human)
Gene Length963
Protein NamesKinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP33176
Gene CardKIF5B
Uniprot IDP33176
PfamPF00225
In ASDyes
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.023077(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1BG2  (X-ray  1.80A  1MKJ  (X-ray  2.70A  2P4N  (EM  9.00A  3J8X  (EM  5.00A  3J8Y  (EM  5.00A  4HNA  (X-ray  3.19A  4LNU  (X-ray  2.19A  5LT0  (X-ray  2.00A  5LT1  (X-ray  1.95A  5LT2  (X-ray  2.60A  5LT3  (X-ray  2.59A  5LT4  (X-ray  2.88A  6OJQ  (EM  3.67A 
DBSNP NA 
Subcellular location [CC]Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2PQA9}. Cytolytic granule membrane {ECO:0000269|PubMed:24088571}. Lysosome membrane {ECO:0000269|PubMed:22172677, ECO:0000269|PubMed:24088571};
Peripheral membrane protein {ECO:0000305|PubMed:22172677, ECO:0000305|PubMed:24088571};
Cytoplasmic side {ECO:0000305|PubMed:22172677, ECO:0000305|PubMed:24088571}. Note=Uniformly distributed between soma and neurites in hippocampal neurons. {ECO:0000250|UniProtKB:Q2PQA9}.
Mouse PG classificationNA
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