| Gene Information | |
|---|---|
| Gene Name | PSMG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 264 |
| Protein Names | Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000128789 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q969U7 |
| Gene Card | PSMG2 |
| Uniprot ID | Q969U7 |
| Pfam | PF09754 |
| In ASD | no |
| Allosteric Prediction | no (-1.076246717) |
| Ortholog in Animals | Alpaca_ PSMG2 ( ortholog_one2one ) Dog_ PSMG2 ( ortholog_one2one ) GuineaPig_ PSMG2 ( ortholog_one2one ) Mouse_ Psmg2 ( ortholog_one2one ) Rat_ Psmg2 ( ortholog_one2one ) Rabbit_ PSMG2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. {ECO:0000269|PubMed:11854909}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002768(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1323730269 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q9EST4}. |
| Mouse PG classification | NA |
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