| Gene Information | |
|---|---|
| Gene Name | KMT7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 366 |
| Protein Names | Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.364) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8WTS6 |
| Gene Card | SETD7 |
| Uniprot ID | Q8WTS6 |
| Pfam | PF02493; PF00856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in pancreatic islets. {ECO:0000269|PubMed:16141209}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.026087(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1H3I (X-ray 2.10A ) 1MT6 (X-ray 2.20A ) 1MUF (X-ray 2.26A ) 1N6A (X-ray 1.70A ) 1N6C (X-ray 2.30A ) 1O9S (X-ray 1.75A ) 1XQH (X-ray 1.75A ) 2F69 (X-ray 1.30A ) 3CBM (X-ray 1.69A ) 3CBO (X-ray 1.65A ) 3CBP (X-ray 1.42A ) 3M53 (X-ray 1.85A ) 3M54 (X-ray 1.60A ) 3M55 (X-ray 1.55A ) 3M56 (X-ray 1.65A ) 3M57 (X-ray 1.70A ) 3M58 (X-ray 1.40A ) 3M59 (X-ray 1.70A ) 3M5A (X-ray 1.75A ) 3OS5 (X-ray 1.69A ) 3VUZ (X-ray 2.50A ) 3VV0 (X-ray 2.00A ) 4E47 (X-ray 2.00A ) 4J7F (X-ray 1.59A ) 4J7I (X-ray 2.56A ) 4J83 (X-ray 1.70A ) 4J8O (X-ray 1.63A ) 4JDS (X-ray 1.70A ) 4JLG (X-ray 1.90A ) 5AYF (X-ray 2.00A ) 5EG2 (X-ray 1.55A ) 5YLT (X-ray 1.69A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:11779497}. Chromosome {ECO:0000305|PubMed:11850410}. |
| Mouse PG classification | NA |
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