Gene Information
Gene NameKLRC4
OrganismHomo sapiens (Human)
Gene Length158
Protein NamesNKG2-F type II integral membrane protein (NK cell receptor F) (NKG2-F-activating NK receptor)
Target NameNA
Target TypeNA
Gene Age25 ( ENSG00000183542 )
Evolutionary StageMammalia
AlphaFoldDBO43908
Gene CardKLRC4
Uniprot IDO43908
PfamNA
In ASDno
Allosteric Predictionno (-1.444215149)
Ortholog in AnimalsAlpaca_ KLRC4 ( ortholog_one2one )
Mouse_ Clec2m ( ortholog_many2many )
Mouse_ Klri1 ( ortholog_many2many )
Mouse_ Klri2 ( ortholog_many2many )
Mouse_ Klre1 ( ortholog_many2many )
Rat_ RGD1564770 ( ortholog_many2many )
Rat_ Klri1 ( ortholog_many2many )
Rat_ Klri2 ( ortholog_many2many )
Rat_ Klre1 ( ortholog_many2many )
OhnologsNA
ParalogsCD69, CLEC12A, KLRC3, KLRC2, CLEC12B, OLR1, KLRG2, CLEC2A, KLRF1, CLEC1A, KLRF2, KLRD1, CLEC2B, KLRC1, CLEC2L, KLRG1, CLEC9A, CLEC1B, KLRK1, CLEC5A, CLEC2D, CLEC7A, KLRB1
TissueNA
Tissue SpecificityNatural killer cells.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1841958  rs2617170 
Subcellular location [CC]Membrane;
Single-pass type II membrane protein.
Mouse PG classificationNA
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