Gene Information
Gene NameCOMTD1
OrganismHomo sapiens (Human)
Gene Length262
Protein NamesCatechol O-methyltransferase domain-containing protein 1 (EC 2.1.1.-)
Target Namecatechol o-methyltransferase domain-containing protein 1
Target TypeNA
Gene Age1064 ( ENSG00000165644 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ86VU5
Gene CardCOMTD1
Uniprot IDQ86VU5
PfamPF01596
In ASDno
Allosteric Predictionno (-0.807647883)
Ortholog in AnimalsAlpaca_ COMTD1 ( ortholog_one2one )
Dog_ COMTD1 ( ortholog_one2one )
GuineaPig_ COMTD1 ( ortholog_one2one )
Mouse_ Comtd1 ( ortholog_one2one )
Pig_ COMTD1 ( ortholog_one2one )
Rat_ Comtd1 ( ortholog_one2one )
Rabbit_ COMTD1 ( ortholog_one2one )
OhnologsNA
ParalogsTOMT, COMT
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2AVD  (X-ray  1.70A 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type II membrane protein {ECO:0000305}.
Mouse PG classificationNA
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