| Gene Information | |
|---|---|
| Gene Name | KLP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1388 |
| Protein Names | Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NS87 |
| Gene Card | KIF15 |
| Uniprot ID | Q9NS87 |
| Pfam | PF15908; PF00225 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in testis, colon, thymus and in breast cancer. {ECO:0000269|PubMed:12747765}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BN2 (X-ray 2.70A ) 6ZPH (EM 6.90A ) 6ZPI (EM 4.50A ) 7RYP (EM 4.80A ) |
| DBSNP | rs34862960 rs11710339 rs3804583 rs17076986 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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