| Gene Information | |
|---|---|
| Gene Name | KLK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 254 |
| Protein Names | Kallikrein-4 (EC 3.4.21.-) (Enamel matrix serine proteinase 1) (Kallikrein-like protein 1) (KLK-L1) (Prostase) (Serine protease 17) |
| Target Name | kallikrein-4 |
| Target Type | Patented-recorded target |
| Gene Age | 101 ( ENSG00000167749 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y5K2 |
| Gene Card | KLK4 |
| Uniprot ID | Q9Y5K2 |
| Pfam | PF00089 |
| In ASD | yes |
| Allosteric Prediction | yes (0.697358119) |
| Ortholog in Animals | Alpaca_ KLK4 ( ortholog_one2one ) Dog_ KLK4 ( ortholog_one2one ) GuineaPig_ KLK4 ( ortholog_one2one ) Macaque_ KLK4 ( ortholog_one2one ) Mouse_ Klk4 ( ortholog_one2one ) Pig_ KLK4 ( ortholog_one2one ) Rat_ Klk4 ( ortholog_one2one ) Rabbit_ KLK4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KLK5, KLK7, KLK3, KLK2, KLK8, KLK1, KLK11, KLK14, KLK12, PRSS58, TMPRSS4, PRSS54 |
| Tissue | prostate |
| Tissue Specificity | Expressed in prostate. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BDG (X-ray 1.95A ) 2BDH (X-ray 3.00A ) 2BDI (X-ray 3.00A ) 4K1E (X-ray 1.30A ) 4K8Y (X-ray 1.00A ) 4KEL (X-ray 1.15A ) 4KGA (X-ray 2.32A ) 6KBR (X-ray 2.00A ) 6NVB (X-ray 1.64A ) 6O21 (X-ray 1.15A ) 7JOD (X-ray 1.33A ) 7JOE (X-ray 2.60A ) 7JOS (X-ray 2.10A ) 7JOW (X-ray 1.91A ) 7JQK (X-ray 1.33A ) 7JQN (X-ray 1.50A ) 7JQO (X-ray 1.60A ) 7JQV (X-ray 2.10A ) |
| DBSNP | rs1654551 rs34626614 rs2569527 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |