| Gene Information | |
|---|---|
| Gene Name | KLK10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 276 |
| Protein Names | Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000129451 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O43240 |
| Gene Card | KLK10 |
| Uniprot ID | O43240 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.762969813) |
| Ortholog in Animals | Alpaca_ KLK10 ( ortholog_one2one ) Dog_ KLK10 ( ortholog_one2one ) GuineaPig_ KLK10 ( ortholog_one2one ) Mouse_ Klk10 ( ortholog_one2one ) Pig_ KLK10 ( ortholog_one2one ) Rat_ Klk10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HGFAC, F7, C1R, F9, F12, F10, CFI, CFD, PRSS55, PRSS51, C1S, C1RL, HP, HPR, KLKB1, F11 |
| Tissue | esophagus, esophagus.mucosa |
| Tissue Specificity | Expressed in breast, ovary and prostate. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LPE (X-ray 2.65A ) 5LPF (X-ray 2.70A ) |
| DBSNP | rs3745535 rs2075690 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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