| Gene Information | |
|---|---|
| Gene Name | KLHLX |
| Organism | Homo sapiens (Human) |
| Gene Length | 609 |
| Protein Names | Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9Y2M5 |
| Gene Card | KLHL20 |
| Uniprot ID | Q9Y2M5 |
| Pfam | PF07707; PF00651; PF01344 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5YQ4 (X-ray 1.58A ) 6GY5 (X-ray 1.09A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, perinuclear region. Nucleus. Golgi apparatus, trans-Golgi network. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Localizes in the perinuclear region in normal conditions. Following IFN-alpha or IFN-gamma treatment, it is relocalized and sequestrated to the PML nuclear bodies, preventing DAPK1 ubiquitination (PubMed:20389280). {ECO:0000269|PubMed:20389280}. |
| Mouse PG classification | NA |
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