| Gene Information | |
|---|---|
| Gene Name | KLHL7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 586 |
| Protein Names | Kelch-like protein 7 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000122550 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IXQ5 |
| Gene Card | KLHL7 |
| Uniprot ID | Q8IXQ5 |
| Pfam | PF07707; PF00651; PF01344 |
| In ASD | no |
| Allosteric Prediction | no (-1.652794933) |
| Ortholog in Animals | Alpaca_ KLHL7 ( ortholog_one2one ) Dog_ KLHL7 ( ortholog_one2one ) GuineaPig_ KLHL7 ( ortholog_one2one ) Macaque_ KLHL7 ( ortholog_one2one ) Mouse_ Klhl7 ( ortholog_one2one ) Pig_ KLHL7 ( ortholog_one2one ) Rat_ Klhl7 ( ortholog_one2one ) Rabbit_ KLHL7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KLHL40, KLHDC7B, GAN, BACH1, KLHL20, KLHL10, KLHL42, KLHL21, KLHL32, KBTBD7, KBTBD6, BACH2, KLHL30, KLHL15, KLHL38, KLHL41, KLHL26, KLHL17, KBTBD3, KLHL13, KLHL9, KLHL18, KLHL23, KLHDC7A, KLHL31, IVNS1ABP, KLHL1, KEAP1, KLHL8, KLHL2, KLHL29, KBTBD12, KLHL34, KLHL33, KLHL36, KLHL28, KBTBD11, KLHL14, CCIN, BTBD18, IPP, KLHDC8B, KLHL6, KLHL24, KLHL5, KBTBD13, KBTBD8, KLHL3, KLHL35, KLHL22, KBTBD2, KLHL12, KLHL4, KLHDC8A |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis. {ECO:0000269|PubMed:16918702}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3II7 (X-ray 1.63A ) |
| DBSNP | rs137853112 rs137853114 rs137853113 rs1227070758 rs879255558 rs780705654 rs879255556 rs17147682 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16918702}. Cytoplasm {ECO:0000269|PubMed:27392078}. Note=Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm. {ECO:0000269|PubMed:27392078}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |