| Gene Information | |
|---|---|
| Gene Name | CAVIN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 425 |
| Protein Names | Caveolae-associated protein 2 (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein) (Serum deprivation-response protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000168497 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95810 |
| Gene Card | CAVIN2 |
| Uniprot ID | O95810 |
| Pfam | PF15237 |
| In ASD | no |
| Allosteric Prediction | no (-0.572256795) |
| Ortholog in Animals | Alpaca_ CAVIN2 ( ortholog_one2one ) GuineaPig_ CAVIN2 ( ortholog_one2one ) Macaque_ CAVIN2 ( ortholog_one2one ) Mouse_ Cavin2 ( ortholog_one2one ) Pig_ CAVIN2 ( ortholog_one2one ) Rat_ Cavin2 ( ortholog_one2one ) Rabbit_ CAVIN2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CAVIN3, CAVIN4, CAVIN1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. {ECO:0000269|PubMed:10191091}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35012125 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:10191091, ECO:0000269|PubMed:2390065}. Membrane, caveola {ECO:0000269|PubMed:19262564, ECO:0000269|PubMed:19525939}. Note=Localizes in the caveolae in a caveolin-dependent manner. {ECO:0000269|PubMed:19262564}. |
| Mouse PG classification | NA |
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