Gene Information
Gene NameKLHL17
OrganismHomo sapiens (Human)
Gene Length642
Protein NamesKelch-like protein 17 (Actinfilin)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000187961 )
Evolutionary StageEumetazoa
AlphaFoldDBQ6TDP4
Gene CardKLHL17
Uniprot IDQ6TDP4
PfamPF07707; PF00651; PF01344
In ASDno
Allosteric Predictionno (-1.233130671)
Ortholog in AnimalsAlpaca_ KLHL17 ( ortholog_one2many )
Dog_ KLHL17 ( ortholog_one2one )
GuineaPig_ KLHL17 ( ortholog_one2one )
Macaque_ KLHL17 ( ortholog_one2one )
Mouse_ Klhl17 ( ortholog_one2one )
Pig_ KLHL17 ( ortholog_one2one )
Rat_ Klhl17 ( ortholog_one2one )
OhnologsKLHL28
ParalogsKLHL40, KLHDC7B, GAN, BACH1, KLHL20, KLHL10, KLHL42, KLHL21, KLHL32, KBTBD7, KBTBD6, BACH2, KLHL30, KLHL15, KLHL38, KLHL41, KLHL26, KBTBD3, KLHL13, KLHL9, KLHL18, KLHL23, KLHDC7A, KLHL31, IVNS1ABP, KLHL1, KEAP1, KLHL8, KLHL2, KLHL29, KBTBD12, KLHL34, KLHL7, KLHL33, KLHL36, KLHL28, KBTBD11, KLHL14, CCIN, BTBD18, IPP, KLHDC8B, KLHL6, KLHL24, KLHL5, KBTBD13, KBTBD8, KLHL3, KLHL35, KLHL22, KBTBD2, KLHL12, KLHL4, KLHDC8A
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6HRL  (X-ray  2.60A 
DBSNP NA 
Subcellular location [CC]Postsynaptic density {ECO:0000250|UniProtKB:Q8K430}. Synapse {ECO:0000250|UniProtKB:Q8K430}.
Mouse PG classificationNA
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