| Gene Information | |
|---|---|
| Gene Name | KLHDC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Kelch domain-containing protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000197776 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N7A1 |
| Gene Card | KLHDC1 |
| Uniprot ID | Q8N7A1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.409722779) |
| Ortholog in Animals | Alpaca_ KLHDC1 ( ortholog_one2one ) Dog_ KLHDC1 ( ortholog_one2one ) GuineaPig_ KLHDC1 ( ortholog_one2one ) Macaque_ KLHDC1 ( ortholog_one2one ) Mouse_ Klhdc1 ( ortholog_one2one ) Pig_ KLHDC1 ( ortholog_one2one ) Rat_ Klhdc1 ( ortholog_one2one ) Rabbit_ KLHDC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HCFC2, KLHDC4, FBXO42, KLHDC2, KLHDC3, KLHDC9, KLHDC10, RABEPK, LZTR1, HCFC1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with high levels in skeletal muscle, pancreas and liver. Undetectable in peripheral blood leukocytes. {ECO:0000269|PubMed:16964437}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:16964437, ECO:0000269|PubMed:32200094}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |