| Gene Information | |
|---|---|
| Gene Name | KLF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 283 |
| Protein Names | Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000067082 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99612 |
| Gene Card | KLF6 |
| Uniprot ID | Q99612 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.24437071) |
| Ortholog in Animals | Alpaca_ KLF6 ( ortholog_one2one ) Dog_ KLF6 ( ortholog_one2one ) GuineaPig_ KLF6 ( ortholog_one2one ) Macaque_ KLF6 ( ortholog_one2one ) Mouse_ Klf6 ( ortholog_one2one ) Pig_ KLF6 ( ortholog_one2one ) Rat_ Klf6 ( ortholog_one2one ) Rabbit_ KLF6 ( ortholog_one2one ) |
| Ohnologs | KLF7 |
| Paralogs | KLF17, KLF11, KLF18, SP8, KLF15, KLF13, SP9, SP7, KLF16, KLF5, KLF12, KLF7, KLF3, KLF2, SP5, SP6, KLF8, KLF1, KLF14, KLF10, KLF4, KLF9 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121909142 rs121909139 rs121909141 rs121909144 rs121909143 rs372338890 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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