| Gene Information | |
|---|---|
| Gene Name | KLF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | Krueppel-like factor 4 (Epithelial zinc finger protein EZF) (Gut-enriched krueppel-like factor) |
| Target Name | kruppel like factor 4 |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000136826 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O43474 |
| Gene Card | KLF4 |
| Uniprot ID | O43474 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.080797793) |
| Ortholog in Animals | Alpaca_ KLF4 ( ortholog_one2one ) Dog_ KLF4 ( ortholog_one2one ) GuineaPig_ KLF4 ( ortholog_one2one ) Macaque_ KLF4 ( ortholog_one2one ) Mouse_ Klf4 ( ortholog_one2one ) Pig_ KLF4 ( ortholog_one2one ) Rat_ Klf4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KLF17, KLF11, KLF18, SP8, KLF15, KLF13, SP9, SP7, KLF16, KLF5, KLF12, KLF7, KLF3, KLF2, SP5, SP6, KLF8, KLF1, KLF14, KLF6, KLF10, KLF9 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);0.080000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VTX (X-ray 2.14A ) |
| DBSNP | rs1059913 rs1059914 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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