| Gene Information | |
|---|---|
| Gene Name | TIMP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 220 |
| Protein Names | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000035862 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P16035 |
| Gene Card | TIMP2 |
| Uniprot ID | P16035 |
| Pfam | PF00965 |
| In ASD | no |
| Allosteric Prediction | yes (0.685296404) |
| Ortholog in Animals | Alpaca_ TIMP2 ( ortholog_one2one ) GuineaPig_ TIMP2 ( ortholog_one2one ) Macaque_ TIMP2 ( ortholog_one2one ) Mouse_ Timp2 ( ortholog_one2one ) |
| Ohnologs | TIMP3 |
| Paralogs | TIMP1, TIMP4, TIMP3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1BR9 (X-ray 2.10A ) 1GXD (X-ray 3.10A ) 2TMP (NMR - ) 4ILW (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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